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The following abstracts were presented at the XIV International Symposium on Respiratory and Viral Infections by the Chairs and The Macrae Foundation’s Scientific Advisory Board. These abstracts represent cutting-edge research in the field of respiratory viral infections and reflect topics covered at the meeting: Animal/Human interface, virology/diagnostics, pathogenesis, epidemiology/impact, clinical, antivirals and therapeutics, and vaccinology/prevention.

I – 1 Martha Nelson Rates and Patterns of Genomic Reassortment of Influenza Viruses in North American Swine
I – 2 Yeny Tinoco Young Investigator Recipient
Cross-species Transmission of Pandemic Influenza (pH1N1) Virus in Backyard Pig Famrs in Semirural Communities in Tumbes, Peru
I – 3 Eman Abd Elkreem Study of Avian Influenza Infection among Vaccinated and Non Vaccinated Bird Flocks in Egypt, 2007–2009
II – 1 Catherine Beauchemin Young Investigator Recipient
Characterization of the Fitness Impairments Induced by the H275Y Oseltamivir-resistance Mutation in the Influenza A/Brisbane/59/2007 and 2009 Pandemic H1N1 Backgrounds
II – 2 Rachel A Ochola The Burden and Viral Etiologies of Severe Respiratory Illness in Rural Western Kenya, 2009 – 2011
II – 3 Paola Cristina Resende Young Investigator Recipient
Detection of Polymorphisms at Residue 222 of the Pandemic Influenza A/H1N1 Hemagglutinin at Quasi-species Level: Association with Severe Cases
II – 4 Christopher W. Wong Pan-Pathogen Diagnostics – Insights from Clinical Validation Trials
III – 1 Irina V. Alymova The PB1-F2 Protein Proapoptotic Sequence Contributes to Influenza A Virus Pathogenicity and Predisposition to Secondary Bacterial Infection
III – 2 John Nicholls The Influence of Smoking on Pulmonary Influenza Infection – an Ex Vivo Study
III – 3 Peter Wark Deficient Antiviral responses to Influenza in Primary Bronchial Epithelial Cells of Chronic Obstructive Pulmonary Disease
III – 4 Nelson Lee Role of Toll-like Receptors in Naturally Occurring Influenza
III – 5 Matthijs R.A. Welkers Viral Quasispecies Evolution of 2009 pH1N1 Influenza Virus during Serial Passaging in Differentiated Normal Human Airway Epithelial Cells
IV – 1 Frank Coenjaerts The Role of Respiratory Viruses in Lower Repiratory Tract Infections in Primary Care
IV – 2 H. Rogier van Doorn A Large Epidemic of Enterovirus 71 Associated Hand, Foot and Mouth Disease in Southern Vietnam, 2011
IV – 3 Adriana Kajon Molecular Epidemiology of Adenovirus 4 and 7 Infections of Military Recruits in Training during the 15 years with no Vaccination Program (1997-2011)
IV – 4 Philip Spagnuolo A Retrospective, Observational Study on Incidence, Influenza-Associated Complications and Treatment Patterns of Influenza in the United States: 2006–2010 Influenza Seasons
IV – 5 Cecile Viboud Spatial Epidemiology of Respiratory Syncytial Virus (RSV) in the USA
IV – 6 Lincoln Lau Individual Variability in Patterns of Viral Shedding in Influenza A Virus Infections
IV – 7 Wladimir J. Alonso Latitudinal Gradients in the Timing and Mortality Burden of the 2009 H1N1 Influenza Pandemic in Brazil
V – 1 Martin Ludwig Carageenan Nasal Spray against Common Cold, a Double Blind Placebo Controlled Prospective Trial
VI – 1 Drew Griffin Levy The Influenza Resistance Information Study (IRIS): Patterns and Predictors of Anti-viral Drug Treatment
VI – 2 Stella Muthuri A Systematic Review on the Impact of Neuraminidase Inhibitor Antiviral use on Outcomes of Public Health Importance during the 2009/10 (swine) Pandemic Influenza A/H1N1v
VI – 3 Barbara Rath Clinical and Virological Response to Oseltamivir in Infants <1 year with Influenza
VI – 4 Norio Sugaya Widespread Use of Neuraminidase Inhibitors in Japan, and Several Issues to Be Resolved
VI – 5 Ahmet Faik Oner
(for Stephen Toovey)
Effectiveness of Oseltamivir in Adults and Adolescents with Seasonal Influenza Taking Symptomatic Therapy: A Retrospective Analysis of RCT Data
VI – 6 Craig Rayner Pharmacokinetic-Pharmacodynamic (PK-PD) Determinants of Oseltamivir Efficacy using Data from Two Phase 2 Inoculation Studies
VI – 7 Jennifer McKimm-Breschkin Screening Neuraminidase Inhibitor Susceptibility of Avian Influenza Isolates from SE Asia 2005-2009 Identifies H5N1 I222 Mutants with Reduced Oseltamivir Sensitivity
VII – 1 Benjamin J. Cowling Efficacy of Seasonal Influenza Vaccination in Children in Hong Kong: a Randomized Controlled Trial
VII – 2 Hongquan Wan Monoclonal Antibodies Cross-reacting with the Neuraminidase of Seasonal and 2009 Pandemic H1N1 Influenza Viruses
VII – 3 Alessandra Vitelli A Novel RSV Genetic Vaccine Candidate based on Chimpanzee Adinovirus and MVA Vectors is Safe and Highly Immunogenic in Rodents and Primates and fully Protects Cotton Rats from RSV Challenge
VII – 4 Louis Fries Safety and Immunogenicity of a Recombinant RSV F Protein Nanoparticle Vaccine Manufactured in Insect Cells: a Phase I Dose and Formulation-finding Trial in Adults
VII – 5 Sumita Roy-Ghanta Immunogenicity and Safety of H1N1 Vaccination in Adults aged 19-40 years Vaccinated with Seasonal Influenza Vaccine 4 Months Previously
VII – 6 Benjamin J. Cowling Evidence of Virus Interference? Increased Risk of Non-influenza Respiratory Virus Infections Associated with Receipt of Inactivated Influenza Vaccine
VII – 7 Xavier Saelens A Novel Human Respiratory Syncytial Virus Vaccine Based on the Extracellular Domain of Small Hydrophobic Protein